搜同

一、个人简介

尹晓畅，男，副研究员

邮箱：[email protected]

研究领域：植物表观遗传学，植物抗逆分子机理和应用研究

硕/博士研究生 招生专业：作物学、农艺与种业

教育背景：                                                                                                                             

2014.09至2018.12， 搜同 ，生物化学与分子生物学，博士；                 

2011.09至2014.06， 搜同 ，作物遗传育种，硕士；
2006.09至2010.06，吉林农业大学，生物工程，学士。

工作简历：

2024.01-至今， 搜同 ， 搜同 ，副研究员；

2023.05至2024.01，北京大学现代农业研究院，副研究员；

2020.06至2022.12，北京大学，现代农 搜同 ，博士后。

二、科研概况

近5年发表文章情况

1. Jiayue Shu†, Linhua Sun†, Dingyue Wang†, Xiaochang Yin†, (共同一作) Minqi Yang†, Zhijia Yang, Zheng Gao, Yuehui He, Myriam Calonje, Jinsheng Lai, Xing Wang Deng, Hang He* and Yue Zhou*: EMF1 functions as a 3D chromatin modulator in Arabidopsis. Molecular Cell 2024, 84(24): 4729-4739.

2. Tingting Yang†, Dingyue Wang†, Lingxiao Luo†, Xiaochang Yin†, (共同一作) Zhihan Song, Minqi Yang, Yue Zhou*: PWOs repress gene transcription by regulating chromatin structures in Arabidopsis. Nucleic Acids Research 2024, 52(21): 12918-12929.

3. Xiaochang Yin†, Francisco J. Romero-Campero†*, Minqi Yang†, Fernando Baile, Yuxin Cao, Jiayue Shu, Lingxiao Luo, Dingyue Wang, Shang Sun, Peng Yan, Zhiyun Gong, Xiaorong Mo, Genji Qin, Myriam Calonje* and Yue Zhou*: BMI1 binding and H2AK121ub contribute to shaping local and long-range interactions in Arabidopsis genome. The Plant Cell 2023, 35 (7):2484-2503.

4. Xiaochang Yin†, Francisco J. Romero-Campero†*, Pedro de Los Reyes, Guangmei Tian, XiaoZeng Yang, Xiaorong Mo, Shuangshuang Zhao, Myriam Calonje* and Yue Zhou*: H2AK121ub in Arabidopsis associates with a less accessible chromatin state at transcriptional regulation hotspots. Nature Communications 2021, 12 (1):315.

5. Xiaochang Yin†, Youquan Xia†, Qing Xie†, Yuxin Cao, Zhenyu Wang, Gangping Hao, Jie Song, Yang Zhou* and Xingyu Jiang*: The protein kinase complex CBL10-CIPK8-SOS1 functions in Arabidopsis to regulate salt tolerance. Journal of Experimental Botany 2020, 71 (6):1801-1814.

6. Qing Xie†, Xiaochang Yin†,(共同一作) Yu Wang†, Yuting Qi, Chengcai Pan, Sunnatulla Sulaymanov, Quan Sheng Qiu*, Yang Zhou* and Xingyu Jiang*: The signalling pathways, calcineurin B‐like protein 5 (CBL5)-CBL‐interacting protein kinase 8 (CIPK8)/CIPK24‐salt overly sensitive 1 (SOS1), transduce salt signals in seed germination in Arabidopsis. Plant Cell and Environment, 2024, 47: 1486-1502.

7. Yafei Fan†, Xiaochang Yin†,(共同一作) Qing Xie, Youquan Xia, Zhenyu Wang, Jie Song, Yang Zhou* and Xingyu Jiang*: Co-expression of SpSOS1 and SpAHA1 in transgenic Arabidopsis plants improves salinity tolerance. BMC Plant Biology 2019, 19(1): 74.

8. Yang Zhou†, Xiaochang Yin†,(共同一作) Shumin Wan†, Yanping Hu, Qing Xie, Ruimei Li, Baibi Zhu, Shaoping Fu, Jianchun Guo* and Xingyu Jiang*: The Sesuvium portulacastrum Plasma Membrane Na⁺/H⁺ Antiporter SpSOS1 Complemented the Salt Sensitivity of Transgenic Arabidopsis sos1 Mutant Plants. Plant Molecular Biology Reporter 2018, 36(4): 553-563.

9. Yang Zhou†, Zesen Lai†, Xiaochang Yin†,(共同一作) Shan Yu, Yuanyuan Xu, Xiaoxiao Wang, Xinli Cong, Yuehua Luo, Haixia Xu* and Xingyu Jiang*: Hyperactive mutant of a wheat plasma membrane Na⁺/H⁺ antiporter improves the growth and salt tolerance of transgenic tobacco. Plant Science 2016, 253: 176-186.

10. Yang Zhou†, Xiaochang Yin†,(共同一作) Ruijun Duan, Gangping Hao, Jianchun Guo* and Xingyu Jiang*: SpAHA1 and SpSOS1 Coordinate in Transgenic Yeast to Improve Salt Tolerance. PLoS One 2015, 10(9): e0137447.

11. Zhitong Ren, Runyu Gou, Wanqing Zhuo, Zhiyu Chen, Xiaochang Yin, Yuxin Cao, Yue Wang, Yingjie Mi, Yannan Liu, Yingxiang Wang, Liu-Min Fan, Xing Wang Deng and Weiqiang Qian: The MBD-ACD DNA methylation reader complex recruits MICRORCHIDIA6 to regulate ribosomal RNA gene expression in Arabidopsis. The Plant Cell 2024, 36(4): 1098-1118.

12. Linhua Sun†, Yuxin Cao†, Zhu Li†, Yi Liu, Xiaochang Yin, Xing Wang Deng*, Hang He*, and Weiqiang Qian*: Conserved H3K27me3-associated chromatin looping mediates physical interactions of gene clusters in plants. Journal of Integrative Plant Biology 2023, 65:1966-1982.

13. Jia Shu, Xiaochang Yin, Yannan Liu, Yingjie Mi, Bin Zhang, Aoyuan Zhang, Hongbo Guo and Juane Dong: MBD3 Regulates Male Germ Cell Division and Sperm Fertility in Arabidopsis thaliana. Plants 2023, 12 (14): 2654.

14. Yuxin Cao, Jiayin Wang, Songlin Wu, Xiaochang Yin, Jia Shu, Xing Dai, Yannan Liu, Linhua Sun, Danmeng Zhu, Xingwang Deng, Keqiong Ye and Weiqiang Qian: The small nucleolar RNA SnoR28 regulates plant growth and development through by directing rRNA maturation. The Plant Cell 2022, 34(11): 4173-4190.

15. Tingting Yang†, Dingyue Wang†, Guangmei Tian†, Linhua Sun†, Minqi Yang, Xiaochang Yin, Jun Xiao, Yu Sheng, Danmeng Zhu, Hang He and Yue Zhou:  Chromatin Remodeling Complexes Regulate Genome Architecture in Arabidopsis. The Plant Cell 2022, 34(7): 2638-51.

16. Qingqing Han, Yongping Wang, Jian Li, Jing Li, Xiaochang Yin, Xingyu Jiang, Min Yu, Suomin Wang, Sergey Shabala and Jinlin Zhang: The mechanistic basis of sodium exclusion in Puccinellia tenuiflora under conditions of soil salinity and potassium deprivation. The Plant Journal 2022, 112: 322-338.

17. Yang Zhou, Chenglong Yang, Yanping Hu, Xiaochang Yin, Ruimei Li, Shaoping Fu, Baibi Zhu, Jianchun Guo* and Xingyu Jiang*: The novel Na+/H+ antiporter gene SpNHX1 from Sesuvium portulacastrum confers enhanced salt tolerance to transgenic yeast. Acta Physiologiae Plantarum 2018, 40(3).

近五年主持课题情况：

主持中国博士后科学基金第14批特别资助（站中），经费来源：中国博士后科学基金会，项目编号：2021T140019，项目经费：18万元。